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Showing posts from February, 2017

Predictive risk of Small Intestinal Bacterial Overgrowth (SIBO) in large cohort retrospective study

Predictive risk of Small Intestinal Bacterial Overgrowth (SIBO) in large cohort retrospective study . A total of 1809 patients who tested positive for SIBO using a Lactulose Hydrogen Breath test ( Brechmann, Sperlbaum, & Schmeigel, 2017 ) . The study looked at which pathophysiological exposures had the most predictive risk of SIBO. They used a statistic called odds ratio (OR) . An odds ratio (OR) is a measure of association between an exposure and an outcome. The OR represents the odds that an outcome will occur given a particular exposure, compared to the odds of the outcome occurring in the absence of that exposure .  For example you can see that being exposed to proton pump therapy makes you 1.4 times more likely than those non-exposed to proton pump therapy to develop SIBO.  This is a great study in that addresses the mechanisms that would lead to impaired clearance of bacteria from the small intestine and the subsequent development of SIBO.  Surprisingly that being

Orange Jacket Guy

Sunday I was out for a run and all the sudden I felt a breeze go by my head.  It took me a few minutes before I realized that some guy just blew by me and that was not the wind but rather someone running like a jackrabbit compared to my turtle-like pace. My first reaction was... "wow am I that slow?". Then I looked up and saw who it was. I was so thrilled that this man who used to be completely deconditioned was now sprinting by me at such a rapid pace. I was so inspired that I had to take a photo of his obvious orange running jacket leaving me in the dust. Two years ago I used to cross paths with this same man who's level of exercise intensity was limited to walking at a slower than average pace. Since we always crossed paths on the same route I would say hello or wave. Sometimes when I would be driving by and see him out for a walk I would wave and give him a "thumbs up". Over time I have seen his diligent commitment transform him from walker to runner. His bo