A study using a commonly prescribed probiotic called VSL#3 showed that male IBS sufferers using VSL#3 had less abdominal pain and an improved satisfaction with bowel habits. (Wong.2015) It is interesting that patients in the study that used the probiotic had increased morning salivary melatonin. This study is very useful in helping explain another reason why taking a probiotic is regulatory for the digestive system. My overly simplistic surmise of what is happening is that this probiotic is favorably shifting the gut biome so that the enterochromaffin cells are secreting melatonin more efficiently. Melatonin (a hormone) has been studies in the digestive tract as it is known to be produced by enterochromaffin cells and small amounts stimulate motility and large amounts seem to slow motility. As we know Melatonin is also produced in the body by the pineal gland and is responsible for helping with sleep/wake cycles of the body’s biorhythm. It also boosts natural killer cell activity ...
The Blog of Sound Integrative Health . The Kirkland, Washington Naturopathic Medicine clinic.